Abstract: The general goal of this investigation was to analyse the institutional components influence on take-up of VMMC in Busia County. Voluntary Medical Male Circumcision (VMMC) is the surgical removal of the foreskin by a trained health worker. This study utilized blended techniques configuration including both subjective and quantitative approaches. The study focused on male populace from 20 years and above. The population for this study was 276 respondents.