Abstract: Members of Persea are typically medium-size trees, 15-30 meters tall at maturity with leaves that are simple, lanceolate to broad and flowers arranged in short panicles, with six small greenish-yellow perianth segments 3-6mm long, nine stamens, and an ovary with a single embryo. The aim of this work is to identify the chemical compounds in dichloromethane and methanol (2:1) and screened for phytochemicals in Persea americana root extracts. Solvent extraction was used to extract crude extracts from the root and the crude extracts were subjected to Gas Chromatography-Mass Spectroscopy (GC-MS) analysis and phytochemical screening. The result showed that hundred chemical compounds were identified but eleven are the major which are correlated with NIST library in which the correlation percentage (%) was taken from 18-100%.