Abstract: Helicobacter pylori infection is the most common chronic bacterial infection around the world. It is a major aetiological factor in chronic gastric carcinoma and gastric mucosal associated lymphoid tissue lymphoma. A study on the prevalence of Helicobacter pylori was carried out among 204 clients comprised 118 males and 86 females aged 11- 50years between September,2019 to march,2020.Blood samples were collected from clients and analyzed to determine the presence of Helicobacter pylori using Global Device H.pylori Antibody Rapid test cassette. Out of 204 clients screened 120 (58.8%) were positive for Helicobacter pylori. The result shows that males were more infected than females with 64(31.4%) and 56(27.4%) positive cases respectively.