Abstract: The study assessed implication of HIV/AIDs on household income in Dodoma Municipal. A sample of 150 respondents was purposively and randomly selected and a case study design was adopted. Primary and secondary data were collected. The qualitative and Quantitative data were analysed by using the MS-Excel. The results showed that majority of the respondents (60%) engaged themselves in farming and gardening. Also, findings revealed that the respondents whose monthly income was below Tshs.100, 000/= or the equivalent of $ 60 spent a great portion of their income on transport and medication, while those who earn income above Tshs. 100,000/= spent a great portion of their income on special food and transport