IJSRP, Volume 2, Issue 11, November 2012 Edition [ISSN 2250-3153]
G.Ravi, Prof.A.Ravinder Nath, Jampaiah Amanaganti, Ch.Sathish Kumar
Using selected theoretical methods the affinity of a large range of bases towards model cations has been quantified. The range of model cations includes the methyl cation as the smallest carbon-centered electrophile, the benzhydryl and trityl cations as models for electrophilic substrates encountered in base-catalyzed synthetic procedures, and the acetyl cation as a substrate model for acyl-transfer reactions. Affinities towards these cationic electrophiles are complemented by data for base addition to Michael acceptors as prototypical neutral electrophiles.