Abstract: Access to essential drugs is very vital to the good performance of the health care delivery system all over the world. The procurement of safe, effective and affordable essential drugs of good quality in the right quantity to the whole population in particular the poor is a priority in health as drug policy. The study was aimed at investigating the factors influencing procurement and utilization of essential drugs at primary health care centres in Shira Local Government Area of Bauchi State. The survey approach was used for this study; via random sampling technique. The researcher collected all the relevant data from primary source. The use of percentages, table and chi-square are employed to organize data collected via SPSS version 23. The factors influencing procurement and utilization of essential drugs at primary health care Centres are, good or large turn up of patients and good account system, seeking of approval, and the cost of getting approval.