Abstract: Amines are efficiently acylated with anhydrides by using Indion Resin as catalyst and acyclic anhydrides react with an amine and amines of various stereo-electronic factors react with the same rates withan anhydride. No chromatographic separation is needed for isolation of the acylated product.Method was developed for the acylation of amine, andin the presence of catalyticamount of Indion 190 resin. Short reaction time, ambient conditions, simple work-up procedure, high yield, easyavailability, reusability, and use of an eco-friendly catalyst are some of the striking features of the presentprotocol.