Abstract: Nanotechnology involves the application of materials at the nanoscale to new products or processes. The interest in nanomaterials is a result of the extreme dependence of properties (electronic, magnetic, optical, mechanical, etc.) on particle size and shape in the 1-100 nm regime. The 1-100 nm scale is of interest for biological interfaces because objects less than 12 nm in diameter may cross the blood-brain barrier [.Sonavane ,et al;2008 ] and objects of 30nm or less can be endocytosed by cells [Connor,et al; 2005].However the impact of these nanomaterials on environmental health remains unclear.( Maynard,et al;2006).