Abstract: Background: There is a lot of public and professional concern about the irrational use of drugs and so this topic is of significant public and professional interest. MRPs are a significant but avoidable (at least to a certain extent) source of patient morbidity and mortality. Identifying these problems, their causes and the impact and influence of professional interventions, will be of significant benefit to the patient and the health care delivery system and the optimization of pharmaceutical care and therapeutic outcomes.