Abstract: Micro Electric Discharge Machining is a non-traditional machining process which can be used for drilling micro holes in high strength to weight ratio materials. This present research study deals with the single optimization of micro EDM process using Genetic Algorithm. Mathematical models using Response Surface Methodology (RSM) is used to correlate the response and the parameters. The desired responses are minimum tool wear rate. The control parameters considered are pulse on time, peak current and flushing pressure on micro EDM of AISI stainless steel 304. The process control parameters of the machine have to be set at an optimal setting in order to achieve the desired responses.