Abstract: - Environmental pollution as a result of anthropogenic activity has raised the possibility of pollution with heavy metals. A serious threat in general for health of living organisms is pollution with lead, because lead has a wide range of use and it is listed after iron, copper and zinc. The level of inhibition of ALA-D activity in erythrocyte is used as a biological index for exposure to lead not only in human population but also in wild species, which are environmentally exposed to lead.