Abstract: This paper is based on final CRS data for the year 2005-2014 on the 10 leading Medically Certified Causes of Death (MCCD)/International Causes of Death-10 in the Delhi (India) by age, sex, race. The Leading causes of infant, neonatal, and post-neonatal death are not analyzed in this paper. The major objective of paper is “To check the variability of causes of death by ten major diseases over the time period of ten years among the age group of specified causes of death. The overall research work of this paper is fully based on most powerful statistical concept i.e. Analysis of Variance (ANOVA) for better output of CRS data of Certified Leading causes of death.