Abstract: This study aims to examine the influence of Corporate Governance and Ownership Structure on the profitability of Indonesian Banking. The method used is explanatory. The population of this research is banking companies listed on the Indonesian Stock Exchange in 2008-2015. The purposive sampling method is used in the selection of samples to obtain a sample of 28 banking companies with total observations of 224 observational data for 4 years. Based on the hypothesis testing, the result shows that simultaneously Independent Audit Committee, Independent Commissioner and Foreign Ownership affect on profitability (ROA) of the banking industry with the influence 30.25% while the rest of 69.75% influenced by other variable not included in this model. Based on partial hypothesis testing show that partially Independent Audit Committee does not affect on Profitability (ROA) while Independent Commissioner and Foreign Ownership have partial influence to Profitability (ROA) of banking industry.