International Journal of Scientific and Research Publications

IJSRP, Volume 3, Issue 7, July 2013 Edition [ISSN 2250-3153]


Synthesis of New 2-(Substituted Phenyl) -4-(4-Methoxyphenyl) -5- Phenyl -1H- Imidazoles from 4-Methoxybenzil in the Absence of Catalyst
      D.S.Ambadkar , R.M.Kedar
Abstract: In this study new imidazole derivatives were synthesized .The first stage involved preparation of 2-hydroxy-1-(4-methoxyphenyl)-ethan-1-one(C1) by reacting 4-methoxybenzaldehyde with benzaldehyde in presence of sodium cyanide catalyst .The second stage involved the synthesis of 1-(4-methoxyphenyl) -2-phenylethan-1,2-dione(C2) using nitric acid in glacial acetic acid .Finally the compound ( 4a to 4l ) were synthesized using the three-component system ( Compound C2 , Substituted benzaldehyde ,and ammonium acetate) .The structures of all compounds were confirmed by elemental analysis , NMR , IR data and melting point .In conclusion ,this method offer some advantages such as good yield , simple procedure , low cost of chemicals and easy work up .

Reference this Research Paper (copy & paste below code):

D.S.Ambadkar , R.M.Kedar (2018); Synthesis of New 2-(Substituted Phenyl) -4-(4-Methoxyphenyl) -5- Phenyl -1H- Imidazoles from 4-Methoxybenzil in the Absence of Catalyst; Int J Sci Res Publ 3(7) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0713.php?rp=P191488
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