Correlation Expression Of Beclin-1 With Histopathological Grading And Molecular Subtypes In Invasive Breast Carcinoma Of No Special Type

IJSRP, Volume 12, Issue 6, June 2022 Edition [ISSN 2250-3153]

Correlation Expression Of Beclin-1 With Histopathological Grading And Molecular Subtypes In Invasive Breast Carcinoma Of No Special Type

Marlina Sinaga, Betty, Delyuzar

Abstract: Background: Breast cancer is most common cancer in women. Most breast cancers are invasive. Invasive breast carcinoma (IBC) is breast cancer that has infiltrated breast tissue. Beclin-1 is an important component in initiation stage of autophagy. Decreased levels Beclin-1 protein due to Beclin-1 gene deficiency, lead to poor prognosis and decreased overall survival in breast cancer cases, where Beclin-1 protein acts as a tumor suppressor.

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Marlina Sinaga, Betty, Delyuzar (2022); Correlation Expression Of Beclin-1 With Histopathological Grading And Molecular Subtypes In Invasive Breast Carcinoma Of No Special Type; International Journal of Scientific and Research Publications (IJSRP) 12(6) (ISSN: 2250-3153), DOI: http://dx.doi.org/10.29322/IJSRP.12.06.2022.p12605