Abstract: Serum separator tube is composed of synthetic polymer gels designed to separate serum from the formed elements. In line with this, an alternative serum separator gel using 0.25 g/mL concentrated Ipomoea batatas starch extract was produced. Results show that all the samples in the alternative serum separator gel successfully separated the serum from the formed elements. However the serum blood glucose levels using the alternative serum separator gel showed no evidence of agreement [ρϲ = 0.133, CI95%: -0.23 to 0.46] when compared with commercial serum separator tube.