Abstract: Human immune-deficiency virus infection continues to ravage human lives globally. Women, continue to experience higher new infection rate, morbidity, mortality and their quality of life (QoL) is adversely in various dimensions for which they need adequate information behaviour. This study investigated the influence of information behaviour on the quality of life of women living with HIV and receiving HAART. Data was collected from three study centers, using a self- developed questionnaire with a reliability index of 0.85.