Abstract: Poor practices of safety are common in the informal garages in Ghana. Despite advance in technology and easy access to personal protective equipment (PPE), the issue of poor knowledge on the usefulness of personal protective equipment (PPE) still proliferates in most of the informal garages, particular in Odorna garages. The study was to access the basic knowledge on personal safety of three different trade area; automotive mechanics, welders, and autobody sprayers. A total of 13 garages were administered with 50 questionnaires, coupling with interview and observation, data was collected for analysis. Although, majority of the apprentices received basic training from their master craftsmen on the usefulness of personal protective equipment (PPE), only few uses them. Lack of law enforcement of safety practices at the garages has also led to low usage and knowledge of the personal protective equipment since over 90% of workers responded that there is no strict supervision on the use of PPE. Apparently no mechanism is set up to ensure or enforce the observance of safety rules and regulation in the garages. It is recommended that, there should be a mandatory training on personal safety on the usefulness of personal protective equipment (PPE) to master craftsmen and apprentices.