Abstract: Ciprofloxacin is a fluoroquinolone antibiotic that is widely used in anti-infective therapy nowadays because of its broad spectrum of activity and potential therapeutic applications. One of the reasons for its widespread use is the presence of multiresistant pathogens that are solely vulnerable to ciprofloxacin. This drugs potential improved efficacy in the treatment of different community-acquired and nosocomial infections, including as respiratory tract, urinary tract, and skin infections, as well as sexually transmitted diseases, is supported by the existing clinical evidence.