Abstract: The aim of study was to measure serum level of visfatin in impaired glucose tolerance subjects and compare with healthy control subjects. In this study 120 IGT and 120 healthy subjects (age and gender matched) were enrolled. BMI, Glucose, HbA1c, Insulin and Visfatin were assessed. Serum visfatin levels were higher in impaired glucose tolerance subjects compared with healthy controls (4.95±1.81 ng/ml vs 2.91± 1.12 ng/ml, respectively, P<0.0001). Increased levels of visfatin can assess diabetes at an early stage.