Abstract: This study aimed to describe the work ethic Salafi economic actors in the city of Ambon in particular in Batumerah. That since the outbreak of horizontal conflicts in Ambon city, many traders exodus and the city of Ambon. The opportunity was utilized by some members of the Salafis to plunge into the business world. Until now, this group is quite successful in the field of entrepreneurship. In contrast to other entrepreneurs, they are very disciplined to keep praying in congregation five times, in addition to actively follow the teachings of religion every night. This study intends to reveal their work ethic is there a relationship with an understanding of his religion. This study used a qualitative approach. The data collection is done by observation, depth interview with the economic actors Salafi whether related to their motivation in entrepreneurship, entrepreneurial characteristics they nor their ethics in business. The conclusion is that they are motivated by the principle of work as worship to Allah SWT. As of worship, in the behavior of the economy, they are maintaining the ethics and norms set forth in the Qur'an and Sunnah Rasul SAW, so no offense, either against God's rights and human rights.