Abstract: Background: Human immunodeficiency virus (HIV) infection leads to profound and irreversible immunosuppression. Liver function abnormalities are commonly seen in HIV-infected patients, and highly active antiretroviral therapy (HAART) has led to complete modification of the pattern of hepatic events in HIV infection. The early recognition and diagnosis of these events will be helpful for the safe and effective use of HAART and enhance the survival rates among HIV-infected people.