Abstract: A ten (10) weeks polyethene sack experiment was conducted at National Biotechnology Development Agency, South West BIODEC Zonal Centre Owode Yewa South, Ogun state, Nigeria between November 2014 and January 2015 to evaluate the effect of chicken (layer) manure (CLM), cow dungs (CD) and saw dust (SD) mixture on the growth and yield of okra (Ablelmoscus esculentus) in a Completely Randomized Design (CRD) replicated three times. The experiment consisted of three treatments including the control, viz; T1 (50g CLM + 30g (CD) +20g (SD), T2 (30g (CLM) + 50g (CD) +20g (SD) and T3 (no application) as control. Parameters measured included plant height, number of leaves, number of fruits, weight of pod, number of branches, stem girt per plant. Data collected were subjected to a one –way analysis of variance. F-protected Fisher’s Least Significant Difference was used to separate the significant mean at 5percent level of confidence. From the results obtained, there was a significant (P<0.05) difference in the treatment effect on the number of leaves but no significant (P>0.05) difference was computed in all other parameters measured. Application of 30g (CLM) + 50g (CD) +20g (SD) mixture resulted in the highest okra growth and yield parameters among the treatment mixtures and could be demonstrated and disseminated by change agents for adoption by farmers in the study area to improve their okra yields.