Abstract: The research applies performance evaluation of pharmaceutical company in Bangladesh. It means evaluate how well the company performs. The main aim is achieved through ratio analysis of four pharmaceuticals (Beacon, ACI, GSKSmithkline and Square pharmaceutical Limited) companies in Bangladesh. The main data collection from the annual financial reports on Beacon, ACI, GSKSmithkline, and Square pharmaceutical companies in 2014 to 2019. The different financial ratios are evaluated such as liquidity ratios, asset management ratios, profitability ratios, market value ratios, debt management ratios, and finally measure the best performance among the Four companies. The mathematical calculation was establishing for ratio analysis among four companies from 2014-2019.