Abstract: In this study, a new kind of nano hydroxyapatite (nHAp) / polyurethane (PU) nano composite were fabricated for potential use in teeth and bone tissue engineering. Nano hydroxyapatite was successfully synthesized by wet chemical precipitation method. In this work, hydroxyapatite/polyurethane nano composites were synthesized and characterization of the compound were done by using Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectrum (EDS).