IJSRP, Volume 3, Issue 2, February 2013 Edition [ISSN 2250-3153]
V.M. Barot, Sahaj A.Gandhi, Anil Mahato, N.B.Mehta
Chalcone moiety (1,3‐diaryl‐2‐propen‐1‐ones) is the backbone of several antinuclear, cardiovascular and antispasmodic drugs. These groups of compounds constitute an important class of natural products belonging to the flavonoid family. A novel 1-(4-butoxy-2-hydroxy phenyl)-3-(2,5-dimethoxyphenyl) prop-2-en-1-one has been synthesized by chemical method. The product has been confirmed by their chemical analysis IR, 1H NMR and 13C NMR. To explore the structural features of the compound X-Ray diffraction (XRD) pattern has been recorded and it confirms that the title compound, C21H24O5 belongs to monoclinic system with P 2/m space group and the crystallographic parameters are a =22.4642 (0.0756), b = 17.1823 (0.0222), c = 10.3753 (0.0324) Ǻ and β = 92.93 (1.410) °. The final product has been screened for their antimicrobial and fungal activities against different panel of organisms.