International Journal of Scientific and Research Publications

IJSRP, Volume 3, Issue 2, February 2013 Edition [ISSN 2250-3153]


Synthesis, X-ray diffraction study and Antimicrobial study of 1-(4-butoxy-2-hydroxyphenyl)-3-(2,5-dimethoxyphenyl) prop-2-en-1-one
      V.M. Barot, Sahaj A.Gandhi, Anil Mahato, N.B.Mehta
Abstract: Chalcone moiety (1,3‐diaryl‐2‐propen‐1‐ones) is the backbone of several antinuclear, cardiovascular and antispasmodic drugs. These groups of compounds constitute an important class of natural products belonging to the flavonoid family. A novel 1-(4-butoxy-2-hydroxy phenyl)-3-(2,5-dimethoxyphenyl) prop-2-en-1-one has been synthesized by chemical method. The product has been confirmed by their chemical analysis IR, 1H NMR and 13C NMR. To explore the structural features of the compound X-Ray diffraction (XRD) pattern has been recorded and it confirms that the title compound, C21H24O5 belongs to monoclinic system with P 2/m space group and the crystallographic parameters are a =22.4642 (0.0756), b = 17.1823 (0.0222), c = 10.3753 (0.0324) Ǻ and β = 92.93 (1.410) °. The final product has been screened for their antimicrobial and fungal activities against different panel of organisms.

Reference this Research Paper (copy & paste below code):

V.M. Barot, Sahaj A.Gandhi, Anil Mahato, N.B.Mehta (2018); Synthesis, X-ray diffraction study and Antimicrobial study of 1-(4-butoxy-2-hydroxyphenyl)-3-(2,5-dimethoxyphenyl) prop-2-en-1-one ; Int J Sci Res Publ 3(2) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0213.php?rp=P14790
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