Abstract: Several population-based studies report an annual incidence of diabetic foot ulceration in the range of 2% to 3% in IDDM and NIDDM patients, whereas the prevalence varies between 4% and 10% . These studies also indicate a general trend for higher frequencies of ulceration with increasing age and duration of diabetes. A 3-year retrospective cohort study of 8905 patients in a large health maintenance organization who have diabetes reported a 5.8% cumulative incidence of ulceration (approximately 2% per year).