Abstract: Medicinal plants form the largest segment of the biodiversity used by indigenous people. The objective of this study was to preserve the perishing knowledge of traditional home remedies for health care in villages of Maharashtra state of India. Men and women from nineteen villages were interviewed and information collected were documented. Crude drug samples were collected. The rural people used medicinal plants available locally for health care. Plants were used as raw, cooked or decoction forms. All the plants used were identified upto species level. Digital and written documentation were made as well as herbaria are prepared. This study gives scope for use of their time tested remedies by the future generation. In addition it gives scope for reverse pharmacological studies.