Abstract: Kitwe stream is the recipient of the effluents from the industrial Plants and flows into the Kafue River, an extremely important river to the Zambian economy. Samples were taken from the stream at 5 different sites. The stream was studied in an effort to determine by chemical means the water quality at various sites and hence the pollution levels of the stream. The water were analyzed for pH, total dissolved solids and total hardness. The results obtained revealed that the values for pH, total dissolved solids and total hardness were outside the recommended limits of WHO water quality standards. It was therefore, concluded at 5% level of significance that the effluents from industrial Plants have an effect on the pollution levels of the stream.