Abstract: Background: Immunobullous disorders are a group of disorders characterized by autoantibodies directed against various skin autoantigens resulting in blister formation. These disorders maybe further classified as intraepidermal and subepidermal depending on the level of bulla. In cases where clinical and histopathological diagnosis could be very challenging, direct immunofluorescence will help at arriving with an accurate diagnosis. Immunofluorescence techniques help in better understanding and classification of the various immunobullous disorders.