Various substituted 2-aminobenzothiazoles have been synthesized cyclocondensation of various substituted anilines with ammonium thiocyanate in presence of bromine. The title product 5-[(1E)-N-(1,3-benzothiazol-2-yl)ethanimidoyl]-4-(furan-2-yl)-3,4-dihydropyrimidine-2(1H)-thione is synthesized by using 2-aminobenzothiazole. The structure of the synthesized compounds have been established on the basis of their spectral data. All micro-wave synthesized compounds results into good yield as compared to conventional method. Synthesized compounds were screened for their antibacterial activities.
Prachi K. Shinde and Dr. Krishnakant T. Waghamode (2017); Synthesis, Characterization and Antibacterial Activity of Substituted Benzothiazole Derivatives;
Int J Sci Res Publ 7(8) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0817.php?rp=P686713