Abstract: The main purpose of this research was to find out a family environment and depression among drug users and non-users. The 30 drug users and 30 non-users were taken as a sample. The research tool for family environment was measured by Joshi and Vyas (1987). While the tool for depression Back depression inventary (1961) was used. Here t test was applied to check the significance of family environment and depression in drug users and non-users. Results revealed that significant difference in factors of family environment and depression with respect to both drug user and non-user.