Abstract: Introduction: Ischemic heart disease is a common cause of morbidity and mortality worldwide. Acute inferior wall myocardial infarction accounts for 40% all acute myocardial infarctions. Right ventricular infarction is common in patients with acute inferior wall myocardial infacrtion.. Objectives: to study the incidence and clinical profile of right ventricular infarction and inferior wall myocardial infarction. Materials and Methods: Fifty cases of inferior wall infarction were included in the study. patients with history of previous infarction ,bundle branch block, cor-pulmonale and suspected pulmonary embolism were excluded. Results: Incidence of right ventricular infarction is about 40% in inferior wall myocardial infarction. Most patients presented with retrosternal chest pain associated with sweating. Raised JVP, hypotension, bradycardia. Conclusions: Incidence of right ventricular infarction in inferior wall infarction was fairly common. If diagnosis of right ventricular infarction done accurately and treated early prognosis is usually better.