International Journal of Scientific and Research Publications

IJSRP, Volume 7, Issue 3, March 2017 Edition [ISSN 2250-3153]


Insilico Docking of Various Inhibitors of E.Faecalis Folate Pathway
      ARCHANA MOON, DEEBA KHAN, PRANJALI GAJBHIYE & MONALI JARIYA
Abstract: Drug resistance to therapeutic antibiotics pose a challenge to the identification of novel targets and drugs for the treatment of infectious diseases. Infections caused by Enterococcus faecalis are a major health problem. Moreover, among UTI causing enterococci, multi-drug resistant E. faecalis such as vancomycin-resistant strains (VRE) have been reported increasingly in many countries. SMX & TMP are the commonly prescribed inhibitors of DHFR & DHPS, the enzymes of the folate biosynthetic pathway. In this study, insilico docking of various ligands/inhibitors to the Enterococcus faecalis DHFR & DHPS proteins has been performed by using Autodock Suite, version 1.5 6rC2.

Reference this Research Paper (copy & paste below code):

ARCHANA MOON, DEEBA KHAN, PRANJALI GAJBHIYE & MONALI JARIYA (2017); Insilico Docking of Various Inhibitors of E.Faecalis Folate Pathway; Int J Sci Res Publ 7(3) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0317.php?rp=P636292
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