Abstract: The study was designed to investigate the effect of aerobic exercise with carnitine supplementation on reduction of weight, blood pressure and heart rate levels among Haramaya University students subjected to similar intensity, duration, frequency, and type of exercise. Individuals with BMI 25.5 – 30 kg/m2, age 18 - 30 years old, and no impairment or chronic diseases were involved in the study and the training lasted eight weeks.