Abstract: Pampa River is the third longest river in the South Indian state of Kerala. The river is one of the most stressed rivers in Kerala .Water quality of Chengannur segment of Pampa River was determined based on Physical parameters such as TDS,Turbidity,Temperature and Conductivity followed by water quality index. Three study sites were selected. Mean with standard deviation were taken. Two way ANOVA was conducted. The water quality index (WqI) was calculated. The quality index was84 forTDS and 98 forTurbidity during premonsoon and summer . The study shows that water in the Chengannur segment of Pampa river is of moderate quality.