Abstract: Prostate cancer occupies a prominent place among malignant neoplasia of the genitourinary tract, and currently represents the most common neoplasia, being the second most frequent cause of death by cancer in men. Besides PSA, prostatic acid phosphatase, alkaline phosphatase, tumor ploidy, Gleason score, ultrasonography, computed tomography, magnetic resonance imaging, and bone scintigraphy are useful in the work-up of patients with prostate neoplasia. Bone is a preferred, and sometimes the only, site for prostate cancer metastases, which occur in more than 80% of men with advanced prostate cancer. The objective of current study was to study the characteristics of bone isotope scan findings in the evaluation of bone metastasis in patients with prostate carcinoma.