Abstract: Background: A variety of lifestyle modifications including weight loss in the overweight and regular aerobic physical activities have been shown in clinical trials to lower blood pressure in hypertensive patients. This study aims to investigate the effect of physical activities in lowering blood pressure in hypertensive patients subjected to consecutive physical activities training sessions. Method: A sample of 12 female hypertensive patients diagnosed with hypertension for more than one year were purposively selected from those hypertensive patients visited the primary care center for their regular follow up. A laboratory experiment was conducted in April, 2012 at Haramaya University Health Center. Patients whose systolic blood pressure reading < 180 mmHg, and diastolic blood pressure reading < 110 mmHg and heart rate reading <100 b/m were included in the study. Hematological and biochemical tests and systolic and diastolic blood pressure reading was employed for data collection. Data analysis was made using SPSS Version 15.0.