Abstract: The current study focuses on the use of plant growth regulators (gibberellic acid) and Amino acids (proline) with the goal of finding ways to cope with water scarcity and understanding the physiological adaptations of corn plants to drought by using growth regulators and Amino acids. A field study was conducted from March 2014 to June 2014 to investigate the influence of different concentrations of gibberellic acid (100 and 50ppm) and proline (200 and 100 ppm) to reduce the effect of water stress on the some of physiological characteristics of corn (Zea mays L.) under different irrigation levels (25%, 50%, and 75% from Of field capacity). Compared with that in the untreated plants,a considerable improvement was observed in the growth and yield of the corn plants sprayed with different concentrations of gibberellic acid and proline. Specifically, a clear increase was noted in the leaf chlorophyll content, Proline concentration in leaves (ppm) and The percentage of protein in the seeds of the corn plants sprayed with proline (200ppm) and gibberellic acid (100ppm) under water stress irrigations. Corn plants positively responded to the spraying of proline and gibberellic acid and showed high drought tolerance. The corn plants were more tolerant of drought when sprayed with 200 ppm proline and 100 ppm gibberellic acid. The use of gibberellic acid and proline is an innovative and promising way to reduce the impact of drought on plant growth and crop production.