Abstract: Parents of children with mental retardation experiences high level of emotional, financial and physical stress. There are multiple problems of having a mentally retarded child in the family. The problems are mainly related to the social ridicule and social stigma. Feelings of depression are common, particularly when realization of the child’s retardation is recent. Mothers of children with disability have the higher the perception of economic situation and income adequacy, parenting social support, and religious practices, and the lower the symptoms of depression and found that minority mothers showed the higher the religious coping, the lower the symptoms of depression.