Abstract: This study aims to determine the effectiveness of Information Computer Technology (ICT)-based learning packages focusing on calculus courses among college students, and to find a tested learning package model in the ICT-based learning of calculus. This study was developmental research which includes requirements analysis, designing learning packages, and evaluation of the learning package. Design research uses literature study, survey, application of learning packages, evaluation and content analysis. Overall, 35 college students of Department of Mathematics, Faculty of Mathematics and Science, Manado State University who take calculus courses were participated. Data were analyzed using descriptive analysis argumentative. After applied of this model, the results showed that there was increased in learning outcomes and level of understanding of the concept of differential and integral. It was influenced by the type of learning media that applied to the ICT-based learning package, namely the application program camtasia on power point programs. ICT-based learning was a contextual and based on the philosophy of constructivism learning so this study suggests that this model would become very well implemented in calculus. Therefore, more research on the effectiveness of ICT-based learning model is also needed for other majors. (This finding has been presented in the 3rd International Seminar on Quality & Affordable Education, November 2014, in University of Malaya, Kuala Lumpur)