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IJSRP, Volume 9, Issue 12, December 2019 Edition [ISSN 2250-3153]



      Indra Yacob, Delyuzar, Joko S Lukito

Abstract: Myofibroblast is a contractile cell type that has a high capacity to release ECM which will eventually cause fibrosis. TGF-β regulates the development of epithelial-mesenchymal transitions (EMT) and promotes fibrogenesis. TGF-β acts to encode proteins that regulate cell proliferation, differentiation, and growth and play a role in the main pathway of the myofibroblast signaling which will ultimately lead to fibrosis. TGF-β can also act as a tumor promoter through epithelial-mesenchymal transition (EMT) regulation.

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Indra Yacob, Delyuzar, Joko S Lukito (2019); Association of Fibrosis with the Proliferation Index of Liver Malignancy; International Journal of Scientific and Research Publications (IJSRP) 9(12) (ISSN: 2250-3153), DOI: http://dx.doi.org/10.29322/IJSRP.9.12.2019.p9679

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