Abstract: Students Academic performance in College is based on various parameters such as level of understanding, the mental ability of a student to learn their respective subject for study of which chemistry is one of the subject to be learned . As the department of chemistry aims to develop students who are experimental thinkers and researchers which is a point reflected by their academic performance. This study aimed to determine the problems the students encounter while studying Chemistry in Diploma College. the research used a field research method to know the problems the students encountered while studying chemistry and experimental method to know the changes after creative models and presentation were used for students of diploma. Results of the field research showed that the problems encountered were vocabulary, level of understanding, retention of topics in mind. The results obtained from experimental method were growth in academic performance after using creative models and presentation for teaching Chemistry.