Abstract: Abstract- By using the Oguchi approximation(OA), we study a mixed spin-2 and spin-5/2 Blume-Capel Ising ferrimagnet with different single-ion anisotropies on a simple cubic lattice. It has been carried out Oguchi method and calculated the free energy of a mixed spin ferrimagnetic model from the partition function. By minimizing the free energy, it has been obtained the equilibrium magnetizations and the compensation temperatures. The existence and dependence of a compensation temperature on the crystal field is mainly investigated.