Abstract: Hemoglobinopathies are a heterogeneous group of hereditary hemolytic anemias. Thalassemia and sickle cell anemia are the commonest hemoglobinopathies seen in our region. Aim ; to analyse the family members of hemiglibinopathies for carrier status. Material and methods ;Patients visiting our hospital with features of anemia, recurrent attacks of jaundice, splenomegaly were screened for evidence of hemolysis. Their siblings, parents, first cousins,grand parents are also screened for carrier status. Conclusion ;Thirty two people belonging to five families were screened over a period of one year. Of which three cases were sickle cell anemia, one case was thalassemia major, three cases were sickle thaslassemia, twelve cases were carriers, thirteen cases were normal.