Abstract: Introduction: Respiratory distress, an a acute emergency situation requires mechanical ventilatory support and tracheotomy. Rehabilitation with residual pulmonary and neurological means needs critical analysis when adopting customized physical therapy. Aims & Objectives of this original research was to evaluate the impact of pulmonary rehabilitation on quality of life of this subject. Materials & Methodology: After gradual weaning and the subject getting discharged to home daily domiciliary physiotherapy from 10.02.2017 to 28.05.2017 and he was getting treated at the rehabilitation centre as an outpatient from 1.06.2017 till 30.09.2017 with twice a week frequency in Chennai with principles of pulmonary rehabilitation. Results of pre and post PR were analyzed on QOL SF 36 P<.01 Conclusion: periodical evaluation, feedback, functional activity based exercises, combining pulmonary and neurological therapy can facilitate due rehabilitation in a shorter time frame.