Abstract: Bali as a barometer of Indonesian tourism has been hit hard by Covid-19. The impact on micro, small and medium-sizes enterprises (MSMEs) is difficult to survive. This study aims to describe the challenges and opportunities faced by MSMEs. The object of research is women entrepreneurs in Bali. Data distribution through questionnaires and online Focus Group Discussion (FGD). The challenges for MSMEs is the importance of certification requirement for business actors even though the conditions are declining due to Covid-19, business licenses and legalities that are still not owned, businesses are reopening with small margins and lack of collaboration with other parties. Meanwhile, the opportunities that exist after Covid-19 are the need for innovative businesses and the availability of matching business digitization that brings together various MSME stakeholders to be able to collaborate such as franchises, consignments and partnerships.