Abstract: Organochlorine pesticides (OCPs) are chemical compound classes based on carbon, classified persistent organic pollutants (POPs), and produced for agricultural purposes. OCPs are used in the cotton-growing, which nowadays is one of these compounds attraction mainstays in Benin, although their use has been banned as a result of the 2001 Stockholm Convention. Indeed, OCPs brought up problems including environmental contamination (soils, sediment, water, air, and biota), hazards to organisms and also human health disorders. Due to their fate solubility and persistence, they were detected in Benin food commodities, food chains and webs (vegetables, meat, milk, fish, crabs, amphibians, birds).