Abstract: Drug related problems are frequent and may result in reduced quality of life and even morbidity and mortality. Many studies have shown that Clinical Pharmacist can effectively identify and prevent clinically significant drug-related problems and that Physician acknowledge and act on the clinical pharmacist’s suggestions for intervention to the drug related problems. A pro-active rather than the reactive approach on the part of that Pharmacist seems prudent for obtaining most benefit. This includes participation of Pharmacist’s in the multidisciplinary team discussion at the stage of ordering and prescribing where all types of drug related problem, including also potential problems, should be discussed.