Abstract: BACKGROUND: Prostatic lesions are common health challenges worldwide with prostate cancer rated as second commonest malignancy in male. Prostate Specific Antigen (PSA) is a sensitive but nonspecific marker for prostatic lesions. Transrectal ultrasonography with Doppler interrogation is an affordable imaging technique that has shown remarkable improvement in differentiating benign from malignant prostatic lesions with the potential of improving its sensitivity and specificity in future.